News | Study Finds Vitamin B12 May Raise Testosterone in Men With Infertility
A new study suggests that increased vitamin B12 intake may reduce testosterone deficiency among men with infertility, offering a potential avenue for improving male reproductive health. Dietary changes may help support male fertility.
Background
Male factors are involved in about 30% of infertility cases, and declining male fertility worldwide has raised widespread concern. Lower testosterone is a major marker of declining male fertility, and an age-independent downward trend has become particularly evident in recent years.
Genetic polymorphisms, endocrine dysfunction, and physical injury have traditionally been considered the primary causes of male infertility. Growing research, however, indicates that lifestyle factors—including smoking, poor nutrition, environmental toxins, and sleep disruption—also play important roles. Improving diet by eating more fruits and vegetables and reducing fat and refined sugar intake may benefit sperm quality.
Methods
Published in The Journal of Nutrition, the study analyzed associations between serum vitamin B12 levels and reproductive hormones in 303 men with infertility. Researchers used Spearman rank correlation and linear regression models to examine relationships between vitamin B12 and testosterone, follicle-stimulating hormone (FSH), prolactin, luteinizing hormone (LH), and other hormones.
Results
Men with higher vitamin B12 levels also had higher testosterone levels, showing a clear positive association. Even a moderate increase in vitamin B12 intake was associated with a lower risk of testosterone deficiency. Vitamin B12 showed no significant effect on other hormones such as FSH and LH.
Conclusion
The results show a positive linear association between vitamin B12 and testosterone levels. Men with higher vitamin B12 intake had significantly lower odds of testosterone deficiency. Although the study's cross-sectional design cannot establish causation, the findings provide a new direction for research into the potential role of vitamin B12 in male reproductive health.
News | Study Finds Vitamin B12 May Raise Testosterone in Men With Infertility
News | Study Finds Vitamin B12 May Raise Testosterone in Men With Infertility
A new study suggests that increased vitamin B12 intake may reduce testosterone deficiency among men with infertility, offering a potential avenue for improving male reproductive health. Dietary changes may help support male fertility.
Background
Male factors are involved in about 30% of infertility cases, and declining male fertility worldwide has raised widespread concern. Lower testosterone is a major marker of declining male fertility, and an age-independent downward trend has become particularly evident in recent years.
Genetic polymorphisms, endocrine dysfunction, and physical injury have traditionally been considered the primary causes of male infertility. Growing research, however, indicates that lifestyle factors—including smoking, poor nutrition, environmental toxins, and sleep disruption—also play important roles. Improving diet by eating more fruits and vegetables and reducing fat and refined sugar intake may benefit sperm quality.
Methods
Published in The Journal of Nutrition, the study analyzed associations between serum vitamin B12 levels and reproductive hormones in 303 men with infertility. Researchers used Spearman rank correlation and linear regression models to examine relationships between vitamin B12 and testosterone, follicle-stimulating hormone (FSH), prolactin, luteinizing hormone (LH), and other hormones.
Results
Men with higher vitamin B12 levels also had higher testosterone levels, showing a clear positive association. Even a moderate increase in vitamin B12 intake was associated with a lower risk of testosterone deficiency. Vitamin B12 showed no significant effect on other hormones such as FSH and LH.
Conclusion
The results show a positive linear association between vitamin B12 and testosterone levels. Men with higher vitamin B12 intake had significantly lower odds of testosterone deficiency. Although the study's cross-sectional design cannot establish causation, the findings provide a new direction for research into the potential role of vitamin B12 in male reproductive health.
Source:
Collected online