Guide | Woman Born Without a Uterus Gives Birth After Successful Transplant
A woman born without a uterus gave birth to a baby boy in Alabama, United States. This was reported as the world's first successful pregnancy and birth following a uterus transplant outside a clinical trial.
Officials at the University of Alabama-Birmingham Hospital said the milestone marked important progress for its uterus transplant program and could help support insurance coverage for the treatment.
Uterus transplantation, IVF, and pregnancy can involve up to 50 healthcare professionals and are intended to help women with uterine factor infertility (UFI). An estimated 5% of reproductive-age women worldwide may be affected. Women with UFI cannot carry a pregnancy because they were born without a uterus, underwent a hysterectomy, or have a nonfunctioning uterus.
The woman, Mallory, was diagnosed at age 17 with Mayer-Rokitansky-Küster-Hauser Syndrome, which meant she was born without a uterus. Mallory and her family moved to Birmingham to join the hospital's uterus transplant program. She had previously had a daughter with her sister serving as a surrogate.
The pregnancy followed transplantation of a uterus from a deceased donor. Mallory gave birth to her son in May.
Immunosuppressive Treatment and the Challenges of Uterus Transplantation
“As with other organ transplants, women receiving a uterus transplant must take immunosuppressive medication to prevent rejection,” the hospital program's website states. “After the baby is born, if the woman does not plan another pregnancy, the transplanted uterus is removed by hysterectomy and anti-rejection medication is no longer needed.”
Mallory said in an interview: “People with uterine factor infertility may have several ways to build their families, but a uterus transplant was the option I had always hoped for. Hearing my baby cry was incredible.”
Outlook: Broader Use of Uterus Transplantation
The successful procedure brought hope to Mallory's family and may offer another option for many women worldwide with uterine factor infertility. As the technology matures and becomes more widely available, it may allow more women to carry pregnancies and could support broader insurance coverage.
Guide | Woman Born Without a Uterus Gives Birth After Successful Transplant
Guide | Woman Born Without a Uterus Gives Birth After Successful Transplant
A woman born without a uterus gave birth to a baby boy in Alabama, United States. This was reported as the world's first successful pregnancy and birth following a uterus transplant outside a clinical trial.
Officials at the University of Alabama-Birmingham Hospital said the milestone marked important progress for its uterus transplant program and could help support insurance coverage for the treatment.
Uterus transplantation, IVF, and pregnancy can involve up to 50 healthcare professionals and are intended to help women with uterine factor infertility (UFI). An estimated 5% of reproductive-age women worldwide may be affected. Women with UFI cannot carry a pregnancy because they were born without a uterus, underwent a hysterectomy, or have a nonfunctioning uterus.
The woman, Mallory, was diagnosed at age 17 with Mayer-Rokitansky-Küster-Hauser Syndrome, which meant she was born without a uterus. Mallory and her family moved to Birmingham to join the hospital's uterus transplant program. She had previously had a daughter with her sister serving as a surrogate.
The pregnancy followed transplantation of a uterus from a deceased donor. Mallory gave birth to her son in May.
Immunosuppressive Treatment and the Challenges of Uterus Transplantation
“As with other organ transplants, women receiving a uterus transplant must take immunosuppressive medication to prevent rejection,” the hospital program's website states. “After the baby is born, if the woman does not plan another pregnancy, the transplanted uterus is removed by hysterectomy and anti-rejection medication is no longer needed.”
Mallory said in an interview: “People with uterine factor infertility may have several ways to build their families, but a uterus transplant was the option I had always hoped for. Hearing my baby cry was incredible.”
Outlook: Broader Use of Uterus Transplantation
The successful procedure brought hope to Mallory's family and may offer another option for many women worldwide with uterine factor infertility. As the technology matures and becomes more widely available, it may allow more women to carry pregnancies and could support broader insurance coverage.
Source:
Collected online