Dr. Jan Shifren, United States
     
4.5
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Reproductive Medicine
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Doctor Introduction

Dr. Jan Shifren, United States


Jan Shifren, MD, is a gynecologist, reproductive endocrinologist, and director of the Midlife Women's Health Center at Massachusetts General Hospital. She is the Vincent Trustees Professor of Obstetrics, Gynecology, and Reproductive Biology at Harvard Medical School.

Dr. Shifren specializes in infertility and menopause, caring for women at different stages of life. Her clinical practice is devoted to helping women with infertility build families and assisting midlife women with menopausal concerns. She is a member of the Massachusetts General Hospital Fertility Center and provides assisted reproductive technologies, including ovulation induction and in vitro fertilization (IVF).

Dr. Shifren studied psychology and biology at Yale University and earned her medical degree from Harvard Medical School. She completed her OB/GYN training at Massachusetts General Hospital and Brigham and Women's Hospital, followed by a fellowship in reproductive endocrinology and infertility at the University of California, San Francisco.

Dr. Shifren's research focuses on menopause, including the effects of estrogen, androgens, and replacement therapies on menopausal symptoms, mood, and sexual function. She has written numerous articles and book chapters and presented nationally and internationally on menopause, hormone therapy, female androgens, genitourinary syndrome of menopause, and female sexual function. She is a past president of the North American Menopause Society.

Outside Massachusetts General Hospital, Dr. Shifren enjoys spending time with family and friends, hiking, and traveling.


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55 Fruit St, Boston, MA 02114, United States
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    Featured Reviews
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    Feb 10, 2025
    Great doctors and staff, although some employees are rude and arrogant. That alone does not represent the entire hospital. Unless it is an emergency, I strongly recommend avoiding busy times. I once waited 4 hours in the emergency room.
    Feb 1, 2025
    Massachusetts General Hospital is by far the most incompetent institution I have ever dealt with.
    Jan 30, 2025
    Dr. Husseini is an excellent cardiac surgeon. She is professional, very thorough, easy to communicate with, and most importantly, compassionate toward patients and their families. I would recommend her. Thank you for everything you have done, and thank you to your medical team. Well done, Dr. Husseini, and God bless you!
    Jan 30, 2025
    Kathy Finni, RN, in the emergency department fast track was wonderful! She was patient and professional and smiled at all our silly jokes! If you read this, please let her know, and recognize her nursing director, Melissa Quiñones, for having such an excellent employee!
    Jan 29, 2025
    This was the worst experience of my life. I had severe tooth pain, and they took 6 hours to see me, only to tell me they could not help. Worst hospital, January 29, 2025.
    Feb 20, 2025
    I would leave 0 stars if I could. This hospital failed my mother and put her in danger. Any healthcare professional would have recognized that she was a danger to herself and should have been sectioned. The hospital should have called us if she left. We spoke with several nurses who assured us they would call if she did. She was under their care in room Bigelow 1422A from May 14 to 15, 2023. She was supposed to remain at MGH for several days but was unfortunately discharged on the morning of May 15. There was no call or notification. The next day, May 16, 2023, she was found dead outside Wellington train station; it was also her birthday. Thank you, MGH, for your negligence. I can do nothing about it unless I go to probate court. This organization should be ashamed of itself and how it treats patients. It does not have their best interests at heart and simply rushes them out the door. I will tell everyone I know to avoid this hospital and its affiliates. Horrible, unforgivable, and inhumane.
    Feb 14, 2025
    I just had surgery for kidney cancer and was amazed by the level of service and kindness I received. From the helpful person at the information desk when I first arrived to all the doctors, nurses, and attendants, everyone provided compassionate care, understanding, and assistance before, during, and after my surgery. Thank you to my surgeon, Dr. Wang, and all the other doctors, nurses, nutrition staff, and attendants. Thank you.
    Feb 23, 2025
    I visited this hospital's spine department with Dr. Şençak. Unfortunately, I do not recommend him at all. His diagnostic skills were poor, he was uncooperative, and he did not understand the case. He made an incorrect diagnosis. I ask hospital management to replace this physician with a highly skilled doctor because this is considered an international hospital.
    Jul 19, 2025
    Sept 1st 2018, I had a brain aneurysm rupture and was med flighted from Laconia NH. I had collapsed twice walking out of my bathroom so my 12 year old daughter called 911. Thank God she was still awake at 1:30 am or I wouldn't be here. Laconia EMTS treated me terribly and thought I overdosed. The two men kept telling me multiple times that I need to "stand up" as I was crying on my kitchen floor curled up in a ball holding my head. Laconia EMTs kept asking me how much heroin I took and told me we weren't leaving till I told them how much. My son said "My mom doesn't do drugs". The EMTs snickered and said "yeah ok". I knew I was going to die in front of my children so I used every single ounce of strength that I had to get on the gourney. Yes, two men that easily had well over 50 pounds on me if not more, wouldn't place me on the gurney to get moving. My whole stay at Mass General (all 17 days) was great. I was brought ice cream at 1 am when I couldn't sleep. Since I was bedridden, one nurse "Grace" even washed my hair while I was laying in the bed. She even tried to get the knots out of my hair. She was incredible and such a sweet, caring girl. I was moved up from the ICU to the floor above after 15 days, I was told I'd have more freedom without being hooked up to all the machines. I thought that meant I could go get a soda. I was stopped at the elevators and told I couldn't go off the floor. The woman at the desk who stopped me went out of her way and brought a soda to my room. This hospital and its staff are incredible. They saved my life as most people die before reaching the hospital. I'm incredibly grateful to be alive and the hospital staff made my ENTIRE stay more comfortable. I can't thank you all enough for all you have done for me. Only complaint is one of the social workers. Not the one with the short curly hair..but the other one. She was so rude to my dad. Dr. Mazwi and Dorothy Booth are the most incredible people out there. Much love to you both! Because of you two...I'm still around for my children who need me.
    Jul 8, 2025
    It is already 2025, and Mass General is still conducting inhumane experiments on animals—drilling into monkeys' brains. If your research is so necessary and justified to save human lives, do it on actual humans. Would you find 100 people every day and drill into their brains? No? Not even to supposedly save humanity? You are only doing this to advance your careers. How do you sleep at night?
    Jun 26, 2025
    Jun 23, 2025
    Jun 23, 2025
    Aug 2, 2025
    This happened in 2020 and still affects me every day. I saw a gynecologist after a life-threatening pregnancy. They refused to let my husband hold my hand until I fought back. They never told me how painful it would be, offered no pain relief, and did not even ask whether about 10 students could attend. It was only a uterine biopsy. It was the most painful experience of my life, and I still break down from the psychological trauma. At my most painful moment, 13 people stared as I fell apart and sobbed. If I had known how deeply this would traumatize me even five years later, I would not have let the pregnancy take my life from me. I hate this nightmare and how much it torments me, and all I can do is write this. If you need a gynecologist, do not go here. Heed this warning and protect yourself, because I could not protect myself 💔
    Jul 30, 2025
    Jul 28, 2025
    They made me wait 5 months for an appointment, then another 5 months, and when I arrived, they had canceled it without notifying me! I would give zero stars if I could. The staff are extremely unprofessional.
    Aug 7, 2025
    I called early in the morning, and the female operator was extremely rude, then simply hung up. So rude.
    Aug 4, 2025
    Aug 26, 2025
    Sep 15, 2025
    Sep 9, 2025
    If I could give zero stars, I would. Even with a referral, they repeatedly lose the referral records. It took a year to get an appointment, which was supposed to be today. MyChart showed that I had prepaid over $1,000. They knew the doctor would be away from the clinic for at least a week, yet waited until the Friday before my Monday morning appointment to call and cancel it. I live out of state. The hotel was booked, time off work was arranged, and everything was planned. Another specialist familiar with my condition was also unavailable, but I could see a new doctor in 2026. Now they have to investigate whether the prepayment can be refunded, but no one seems to know how. After not answering the phone today, Patient Relations replied to a message saying it usually takes at least 7 business days, even though I was shown no courtesy throughout this process. Patients should be cautious. I will update or change this review if the situation is resolved more appropriately.
    Sep 8, 2025
    This is a five-star hospital. Our entire family cannot express enough gratitude to the staff, nurses, and doctors for treating our mother with exceptional care and respect. Within minutes of each arrival, nurses and doctors greeted us warmly. Whether or not we were there, they cared for her attentively. We believe their compassionate care and professionalism helped our mother recover so quickly. We will always be grateful to Massachusetts General Hospital. Angels work there.
    Nov 26, 2025
    Nov 24, 2025
    I went there because of a knee injury. They said I had walked too much and could rest in the ER because I had nowhere else to go until the next day. Security then kept harassing me until the security supervisor assaulted me. He pushed me against the door and then forced me outside. I decided to let it go, found somewhere to sit, and zipped my bag. I then discovered that another bag inside it had been searched. Arthur's hospital will only scam you, steal from you, or hurt you.
    Nov 23, 2025
    Dr. Neil Barr, neurogastroenterologist, is the best! I trust his judgment completely! Pat Cardoso
    Nov 22, 2025
    If I could, I would give zero stars. I received care at Massachusetts General Hospital (MGH) throughout my pregnancy and was considered high risk for several reasons. I had early signs of preeclampsia and signs of preterm labor at 36 weeks and 4 days. Although they knew I was high risk, they sent me home when I was already 5 centimeters dilated! I live 50 minutes from the hospital, and the staff knew this. This was also my second child, so labor would typically progress faster. The nurses were extremely rude and arrogant. Because I did not appear to be in much pain and my labor had slowed for 2.5 hours, they forced me to leave. It was absurd. I ultimately had to deliver at a hospital near my home, where I had not wanted to go. I gave birth 13 hours after they discharged me. I was told my baby might not have survived if I had delivered at home or if anything else had gone wrong. I had a placental abruption. Mothers, you know your body better than these doctors do!
    Nov 21, 2025
    The staff are professional, friendly, knowledgeable, and punctual.
    Dec 8, 2025
    My husband, Joe Serrao, has Crohn’s disease and went to the emergency department with a bowel obstruction. He was in severe pain while nurses walked past as though nothing was wrong. I cried and pleaded for help, but they did not respond for two hours. His physician performed surgery and repeated procedures, requiring continual follow-up. After the last procedure, which was supposed to close his stoma, he was not told that he would still have an ostomy bag and pass stool rectally. The emergency department was frightening, with people moved into hallways. I cannot tolerate that place.
    Dec 3, 2025
    Nov 27, 2025
    I had an urgent appointment at Lynn Medical Center today. The clinical staff were outstanding from start to finish, and I have never felt more at ease. Happy Thanksgiving to my care team and family!
    Jan 9, 2026
    I was shocked by this experience. My son was supposed to be transferred to another hospital, but they could not provide any information about the new facility and seemed surprised by my questions. They then canceled the transfer entirely even though I had explicitly asked them not to, delaying my son's treatment. This hospital is dirty, disorganized, and poorly managed. I absolutely do not recommend it.
    Jan 8, 2026
    Can not compare with BWH Very comfortable Very professional Very good organization for . If you’re looking for the highest level of care , medically and emotionally , you don’t need to look any further. Mass General is the place to be.
    Jan 6, 2026
    Good.
    Jan 5, 2026
    Best disaster recovery.
    Jan 27, 2026
    GURDEEP 辛加尔 RAJA SSP
    Jan 15, 2026
    Jan 23, 2026
    The food is better than the service staff. If you have an invisible disability, do not come here.
    Jan 7, 2026
    Mar 13, 2026
    I was told my bill was under review and on hold after I canceled my payment plan and stopped making payments. Yet only one or two weeks later, a collection agency called me about it! My insurer also denied several claims because the hospital failed to submit the required documents, and the hospital then billed me. My daughter's bill was not identified as hers but as mine. A few days after canceling the payment plan, I suddenly received a bill for my daughter's examination, already in collections. They had previously said the bill would not go to collections because it was on hold. This hospital is extortionate!
    Mar 12, 2026
    Had a really disappointing experience with MGH after my wife gave birth (normal delivery, no complications, 2-day stay) and received a bill over $40k with a $4200 deductible. Couple Friends who work with me with same health insurance and coverage had a much better deal at BMC (
    Mar 11, 2026
    I would like to receive all documents concerning atazia. Susan MMille Brockton, Massachusetts 02301
    Mar 6, 2026
    I went there last year and simply want to thank the amazing doctors and nurses who saved my life. I will always be grateful. God bless you.
    Feb 24, 2026
    They allow employees to post extremely disturbing videos on social media. Registered nurse Christina should be fired if she has not been already. She publicly threatened violence against patients who come to this hospital.
    Apr 2, 2026
    Where do I begin? First, I must honestly say that I consider this one of the best hospitals in the country. However, my experience tonight was bizarre and disappointing. Here is what happened. My daughter was in a car accident. Boston police called my wife and me, explained the accident, and said she was at Massachusetts General Hospital (MGH). The officer could not provide many details. We rushed from Providence to Boston to see her. On arrival, we were told only one person could accompany her. In such a critical situation, they allowed only one parent to receive information. The room was easily large enough for two people. While my wife had to process everything the doctor said alone, I could only pace anxiously in the waiting room, worried about my daughter. When the doctor entered to give an update, was one parent really expected to bear that stress alone? Truly sad and disappointing.
    Apr 1, 2026
    Mar 28, 2026
    Every staff member was excellent and caring and showed great compassion toward patients and their families.
    Mar 26, 2026
    Words cannot express my gratitude to Massachusetts General Hospital. They saved my daughter's life. She has a very rare autoimmune disease, and the medical team at MGH was outstanding and began treatment immediately. I will always be grateful for all the care they gave her and the ongoing care she will need. Thank you!
    Mar 16, 2026
    Apr 12, 2026
    I previously saw Dr. Foreman at the metabolic clinic. From the beginning, I had unpleasant interactions with her administrative staff. Nearly all my blood test results were lost, and I had to track them down myself. The staff were inefficient and rude. I complained to both the doctor and the patient advocacy office. The final straw was a carotid ultrasound ordered by Dr. Foreman; I did not receive the results for nearly six months, and the doctor had not reviewed them. This nearly led to a serious problem. They told me there was an issue with my pituitary gland. I was very disappointed and left the clinic to seek a second opinion at a pituitary specialty clinic. That doctor completely rejected Dr. Foreman's diagnosis. After reviewing my blood test results, he told me that a medication Dr. Foreman had said was ineffective was actually working. Ultimately, I lost trust in both doctors. I now receive care elsewhere. I would not return even for a hangnail!
    Apr 27, 2026
    Apr 27, 2026
    Just want to take a moment to review our experience at MGH labor and delivery. We were visiting Boston from out of town. My daughter was advised, from her OB/GYN, to go to the nearest ED after describing symptoms that were out of the norm. We were immediately received with kindness and compassion. She was quickly seen and monitored. The women in the labor and delivery unit were lovely. Jen, Mary, and Suzanne went above and beyond to make my daughter feel safe and comfortable throughout her time there. Kudos to these three individuals as well as everyone else we encountered. We are grateful!
    Apr 24, 2026
    I have been coming to this hospital for more than thirty years and highly recommend it. There is no need to go elsewhere for tests because everything is available here. The restaurant offers a wide variety of food, and the cafeteria is open 24 hours, making it convenient to eat while in the emergency room. The service is first-rate, and all the staff are very kind.
    Jun 19, 2026
    Feb 6, 2025
    Dec 5, 2024
    This hospital has zero respect for court orders or fathers' rights, and the patient and family advocates are a joke. They completely disregarded my rights as a father, then investigated and handled it ‘administratively,’ i.e., personal apologies from the director and manager of the Saugus branch. Idgaf, I will leave a review for every MGH location.
    Sep 17, 2024
    There are 3 Massachusetts General Hospitals here, and every day they send doctors with lethal-injection syringes to the other two hospitals, which do the same. Their blood feud has continued for at least 20 years and is ongoing. I had to hide under the bed constantly because the attending doctors were so incompetent that, for reasons unknown, they mistook a rival doctor for someone who would kill me. I will never return. This is 3 stars rather than 1 because they still removed a 15-inch circumferential obstruction from my rectal cavity.
    Sep 15, 2024
    Bigger hospitals are (not) always better. That is a fact. 😰😰😰
    Sep 11, 2024
    This place is the worst hospital ever. It is a joke.
    Jul 11, 2025
    Jun 24, 2025
    Tell me this: now that the vaccine has been shown not only to lack benefit but to be extremely harmful, should we sue the hospital for forcing us to get the shot? Or were we simply supposed to go without surgery? Massachusetts General Hospital told me I could not have surgery unless I got the shot. Healthcare in Massachusetts has completely deteriorated.
    May 28, 2025
    Massachusetts General Hospital has six or seven buildings of different ages. I really appreciate their care. Everyone explains things patiently.
    Apr 28, 2025
    I want to express my heartfelt gratitude to everyone at the Massachusetts General Hospital Burn Center, Preoperative Center, and Department of Surgery for the outstanding care they provided during my daughter Haley's recent visit. Although her scheduled surgery could not proceed as planned because of an unforeseen medical issue that arose that morning, the entire experience was seamless, calm, and compassionate from the moment we checked in at 5:30 a.m. Haley's preoperative nurse was outstanding: reassuring, attentive, and kind. I was also included in the process and prepared to accompany Haley into the surgical area, which meant a great deal to both of us. When we reached the surgical unit, we received a truly exceptional level of care. Our surgical nurse was wonderful. Haley's anesthesiologist was excellent, and we trusted that she was receiving the best care. My daughter's surgeon, Dr. Hickey, was outstanding. His bedside manner was calm, confident, and kind. He made us feel as though Haley was his only patient that day, which meant the world to us. Every other member of the team, including the residents and surgical staff, was equally amazing. Everyone we encountered demonstrated the highest level of expertise and patient care. Their kindness and professionalism helped turn a highly emotional and uncertain day into one in which I felt embraced, supported, and cared for—not only as a parent, but as a person navigating a complex and stressful situation. Although we left without the outcome we expected, we were deeply grateful to everyone who stood beside us at every step. The care my daughter received and the compassion shown to me were extraordinary. I thank the MGH team for the warmth, clarity, and calm they demonstrated at such a difficult time. Honestly, it made me wonder why anyone in this area would go elsewhere. Your team is exceptional. We thank you from the bottom of our hearts. With sincere gratitude, Tonya Lucas, Haley's mother
    Apr 12, 2025
    Excellent hospital
    Jul 25, 2025
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    Aug 19, 2025
    Massachusetts General Hospital is the worst medical facility. Getting any information about my treatment or results is a nightmare. I had an MRI nearly a week ago and still have no results. It is shocking that review takes this long and feels like medical negligence. If they cannot provide test results or inform patients about their condition, perhaps they should not provide medical care.
    Aug 8, 2025
    I brought my mother here after she had a stroke in early May. Her case was complex and required collaboration between neurology and cardiology. She was hospitalized for about 9 days, and I stayed with her all day, every day. We also spent about 15 hours in the emergency department before she was admitted to neurology. Everyone was wonderful. The medical staff's expertise, kindness, and teamwork impressed me repeatedly. I am confident she recovered, and she has continued doing well since discharge. People travel from across the country to Massachusetts General Hospital, and now I understand why. This place is outstanding. They saved my mother, and I will always be grateful. Many thanks to everyone on Lunder 7.
    Sep 25, 2025
    Sep 16, 2025
    Sep 15, 2025
    Sep 9, 2025
    Terrible experience. The evaluation was incomplete and the treatment inappropriate. After leaving the Massachusetts General Hospital emergency department, I had to see another doctor for proper treatment. They also tried to fraudulently bill a routine emergency visit as an observation admission. This is not the best hospital in the world. Beware!!!
    Nov 8, 2025
    Nov 26, 2025
    Feb 6, 2026
    Christina is a registered nurse in the emergency department. It is astonishing that management allows employees to behave this way. It reflects very poorly on the hospital, especially when your registered nurses cannot be trusted to care for everyone who needs it, regardless of their beliefs.
    Jan 27, 2026
    It saved my life, although their definition of a turkey sandwich is highly questionable.
    Feb 21, 2026
    Employees of this hospital posted violent and threatening statements about U.S. Immigration and Customs Enforcement (ICE) officers on TikTok. I am deeply concerned about this hospital.
    Mar 26, 2026
    Today I tried to book an appointment with my ophthalmologist to check on my glaucoma and get a new eyeglass prescription. NO APPOINTMENTS AVAILABLE UNTIL APRIL 2027!!! Nothing available for any staff ophthalmologist until 2027. MGH Has dropped down to #13 in the national hospital ratings survey. Dropping like a lead weight…what was once the WORLD’s #1 hospital. I repeat…Care Delayed is Care Denied!
    Apr 5, 2026
    May 26, 2026
    Twenty years ago, while I was at Hanscom Air Force Base, I was sent to this hospital for emergency heart surgery. I have continued coming here ever since, driving two hours each time. Over the years, I have seen the quality of service decline. At each cardiology follow-up, a nurse records all updates, then the doctor comes in and leaves after two minutes. There is no opportunity to ask questions unless they affect the next month’s treatment. It is ridiculous. However, my last visit was completely different. Someone was staffing the reception area, and only the doctor was present. It was much better. Your billing department is also terrible. They repeatedly use the wrong codes and submit incorrect information to insurance. My last visit was a follow-up and echocardiogram. Your billing department told my insurer that I had been admitted and discharged. After every visit, I have to spend time working with insurance to correct these errors. Someone needs to determine why the billing department keeps making mistakes.
    May 11, 2026
    Jun 8, 2026
    这是我去过的最糟糕的医院之一，简直是浪费时间。
    Oct 3, 2024
    Sep 8, 2024
    Apr 26, 2022
    Jul 18, 2020
    Feb 12, 2020
    Sep 17, 2024
    A high-quality, caring, comprehensive practice with doctors and staff ready to help. The waiting list for new patients is now over a year.
    Jul 13, 2024
    Aug 2, 2023
    I called to schedule an appointment, and as soon as the receptionist heard that I was a new patient, she hung up.
    Sep 17, 2024
    这是一家非常棒、关怀备至、服务全面的诊所，医生和工作人员总是会抽出时间来解答您的疑问。但加入该诊所的等候名单超过一年。

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