Infertility Center of St Louis, United States
     
4.6
Consultations 49
Reproductive Medicine
Hours: 09: 00 - 16: 00
Clinic Details

We specialize in complex infertility cases, including previous fertilization failure, unsuccessful attempts to achieve pregnancy, and failed vasectomy reversal or IVF. We also treat less complex infertility cases, and patient costs are relatively low compared with most other IVF programs. Patients travel to our St. Louis center from around the world, and we are experienced in making them feel comfortable. We are a full-service fertility clinic located in a hospital consistently rated among the best in America. Our modern facilities are in an elegant, green, non-urban setting with rolling hills, large estate homes, lakes, and clean air. We are a long-established medical center, not a short-lived “egg-freezing” startup that may disappear or be sold.

Our approach is to avoid unnecessary and often costly conventional testing and outdated treatments that may continue for years, leaving couples emotionally and financially exhausted. Instead, we recommend the most effective technology most likely to help the patient become pregnant as soon as possible.

Many couples spend years and thousands of dollars on unnecessary tests with limited scientific validity and no benefit to their treatment plan. They may undergo procedures, such as varicocelectomy in men or laser vaporization of endometriosis in women, that cost time and money without scientifically validated benefits. Inappropriate care and inadequate expertise can be driven by commercial pressures that have worsened the challenges surrounding modern infertility care. Patients should therefore be well informed and ask questions to benefit from modern technology that can help many couples with infertility have a baby.


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Location and Hours
224 S Woods Mill Rd Suite 730, Chesterfield, MO 63017, United States
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  • Monday

    09: 00 - 16: 00

  • Tuesday

    09: 00 - 16: 00

  • Wednesday

    09: 00 - 16: 00

  • Thursday

    09: 00 - 16: 00

  • Friday

    09: 00 - 16: 00

  • Saturday

    Closed

  • Sunday

    Closed

  • Closed Now
    Facilities and More
    • Credit cards accepted
    Doctors at This Clinic

    Reproductive Medicine |

    Years of experience | Consultations 91

    Featured Reviews
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    On-Site Overall Rating

    13 ratings

    • 5 stars
    • 4 stars
    • 3 stars
    • 2 stars
    • 1 stars
    Apr 23, 2026
    Beware!! This doctor violates ASRM guidelines!!
    Jan 30, 2026
    The staff were amazing! They proactively contacted me throughout the process and answered all my questions. Dr. Silber is incredible! Even my husband really liked him.
    Jan 30, 2026
    This place made our dream come true. After 6 years of infertility, we contacted the Silber Infertility Center, and now we have a perfect little boy who is 5 months old!
    Jan 31, 2026
    Forever grateful—truly life-changing care Words cannot express how grateful my wife and I are to Dr. Silber and all the exceptional people who make the Infertility Center of St. Louis what it is today. From the very beginning, starting with the free Zoom consultation, we felt something rare: hope, clarity, and genuine care for us as people who shared the same desire to build a family. That first conversation set the tone, making a journey that had seemed long and difficult feel achievable and medically secure. Lauren, the new patient coordinator, was our first contact and was exceptional: warm, patient with my questions, organized, prompt with emails, and above all kind. She made us feel seen and supported from day one. Dr. DeRosa is brilliant. His expertise is immediately apparent, but what truly distinguishes him is his outstanding communication and exceptional dedication to patients. He was so committed that he answered my call around 9 p.m. on a weekend, months after I had transferred care. He listens, explains, and reassures. In frightening and uncertain moments, he gave us calm and trust, helping us bear the unique, unfamiliar, and sometimes overwhelming stress. With his surgical skill and life experience, Tessa and I always felt confident that we were receiving the best care. Julie in the financial department also deserves special recognition. She was thoughtful, transparent, and tremendously helpful, making a complex, emotional, and expensive process manageable and fair. Her kindness, careful planning, and clear explanations lifted a heavy burden we had not realized we were carrying. Every nurse, coordinator, and staff member treated us with dignity, empathy, and respect. We never felt like a number or simply another new patient to bill. This team has been a precious gift in our lives. Because of them, our family exists in a way that once felt unattainable. We will remain forever grateful and hope to see them again soon!
    Feb 20, 2026
    I wouldn’t recommend coming here. It is super disheartening to hear the way Dr. Silber talks to his staff. Dr. Silber is extremely unprofessional and makes me really uncomfortable.
    Feb 27, 2026
    I am sorry it took me a full year to write this. Juliette turned one on 2/23. I will always be grateful to this clinic, especially Dr. Silber. I traveled from Florida to Missouri specifically for his care, and I would choose him again without hesitation. Because of him, I now have a sweet, happy one-year-old daughter. After a long and emotional journey, he gave me hope. He was compassionate, patient, and knowledgeable, and I truly felt cared for. My daughter is my little angel, all thanks to him and his outstanding team. Thank you for changing my life completely. I will be forever grateful! If possible, I would love to bring her to see the doctor soon. I tried to send photos, but they do not seem to go through. Is there another way to send them? Thank you again! I wish I had found you sooner.
    Dec 2, 2025
    We are very grateful to Dr. Silber, Dr. DeRosa, Dina, and her team for helping us conceive. After three years of infertility, I finally gave birth to our son at age 41. My IVF coordinator Dina communicated very well throughout the process and answered every question. Before the embryo transfer, Dr. Silber was very honest and told me there was only a 30% chance of pregnancy. But it worked! Dr. DeRosa was also very understanding when I cried throughout egg retrieval—not from pain, but because I was emotional! We are very glad we chose this clinic and highly recommend it!
    Dec 10, 2025
    My husband and I struggled with infertility for years and saw many reproductive endocrinologists in the hope of achieving pregnancy. We are very grateful that we found Dr. Silber. The entire process, from consultation to egg retrieval, took only a few months. His team was very kind and attentive. Thanks to Dr. Silber, after a long fertility journey, we finally welcomed our first baby and could not be happier. I highly recommend him!
    May 7, 2025
    Dr. Silberman and his team are amazing! I underwent mini-stimulation IVF, and although the process naturally felt overwhelming, the personalized step-by-step plan he created helped me successfully have twin boys. I am now even considering a second embryo transfer! I am very grateful that I found him and that his clinical expertise helped complete my family.
    Jun 3, 2025
    My husband and I cannot put into words how grateful we are to Dr. Silber, Dr. DeRosa, our IVF coordinator Liz, and the entire staff. Even as I sit here writing this review, I am still amazed that we have a healthy baby boy. After years of infertility, countless surgeries, and almost no hope, we finally found Dr. Silber’s clinic and froze 3 embryos through mini-IVF. Our first embryo transfer was successful, and we have just welcomed our first child! We will always be grateful that we found Dr. Silber. Without him, we would never have experienced the joy of parenthood. Thank you from the bottom of our hearts!
    Aug 10, 2025
    Dr. Silber was sent by God to help us!!! We are so grateful to him and his team! After four unsuccessful IVF cycles at two different clinics in Wisconsin, we had completely lost hope of having another child. We finally found Dr. Silber through Google, and thank God we did! We had an egg retrieval in January 2024, and today our miracle daughter is almost three months old!!! After our 12-year-old son, she is a miracle in our lives. This is all thanks to Dr. Silber and his dedicated team!!! Many thanks to Dr. DeRosa and special thanks to our coordinator Kelsey, who is the best!!!! To everyone reading this, please do not waste your hard-earned money elsewhere. We only wish we had found him sooner.
    Sep 26, 2025
    We had a wonderful experience at the Infertility Center of St. Louis. The clinic assigns a coordinator to your case, which was extremely helpful to me. My coordinator played an important role in helping me keep track of all medications and appointments. She always responded promptly when I had questions. Dr. Silber and Dr. DeRosa clearly and patiently explained each process, and both were very kind and attentive throughout. We also had an excellent experience with ultrasound and laboratory testing at St. Luke’s Hospital. The receptionists always welcomed us warmly and were helpful. The ultrasound and laboratory technicians were friendly and explained the procedures in detail. Egg retrieval and transfer were performed at the Frontenac Surgery Center, where the staff were also courteous and helpful. We had previously undergone one egg retrieval and three failed transfers at another clinic, so this second retrieval was our last hope. Our first transfer with Dr. Silber was successful, and our first baby is due in February. IVF is not easy, and I am grateful for the kindness, patience, and positive attitudes shown by everyone we encountered. Sincerely, Trevor and Lorena Jenkins
    Sep 29, 2025
    If you want a doctor and staff who genuinely care and do not judge you, I would not recommend this place. I will not provide all the details because they concern private matters. Unfortunately, I never met the doctor, but what the staff said was enough for me to cancel my appointment. I have never felt so judged and belittled in my life, especially over something so personal and difficult.

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    • 1 doctor
    • Operating for many years
    • PGT IVF
    • Clinic Address
      224 S Woods Mill Rd Suite 730, Chesterfield, MO 63017, United States

    CDC Success Rates

    Data source: U.S. CDC 2022 Annual ART Report (cumulative live birth rate; new patients across all intended retrievals; own-egg cycles only)

    • Annual Cycles

      863
    • U.S. Median

      511

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    • Preimplantation Genetic Testing and IVF
      Donor Egg or Sperm IVF
      Third-Party Reproduction Information (Subject to Local Law)
      Other