In the United States, sperm donation is regulated at both the federal and state levels. At the federal level, the Food and Drug Administration (FDA) mainly oversees donor screening and processing to ensure donated sperm is safe. State laws differ on donor rights, anonymity, and the legal status of donor-conceived children. Overall, U.S. law tends to protect donor anonymity unless the donor agrees to disclosure, and clearly states that donors do not have support obligations for children born from their sperm. However, state laws vary significantly. For example, some states allow donor-conceived children to seek donor identity information after reaching adulthood, so specific policies may change at any time and should be checked against the latest regulations. The basic process usually includes strict health screening for donors, including genetic history, infectious disease testing, and psychological assessment. Once qualified, sperm is frozen and quarantined for six months for repeat testing. Finally, sperm is distributed to authorized fertility clinics or sperm banks for recipient selection. The process emphasizes voluntary participation and informed consent by the donor, and legal documents must be signed to waive rights and responsibilities toward offspring. Eligible recipients mainly include individuals or couples who need third-party reproductive assistance because of male factor infertility, single women, or same-sex partners. Donors usually must meet basic requirements for age, often 18 to 39, health status, and family history, and pass psychological and legal consultation. Recipients must meet clinic medical and legal requirements, and some states have specific restrictions based on marital status or sexual orientation. Risks and considerations include the legal risk that donor anonymity may be disclosed depending on state law, while recipients must accept the possibility of genetic disease risk from donated sperm, even though screening reduces the likelihood. Donor-conceived children may also seek donor identity after adulthood, causing emotional or legal disputes. All participants should carefully review contract terms and understand state laws on donor responsibility and children's rights. Relevant laws and policies may change at any time. Specific requirements are subject to the country's latest regulations. Consult professional legal and medical advisors.